Similarity between the action of nicotinamide and diazepam on neurotransmitter metabolism in the rat [proceedings].

Values are means? S.E.M. for groups of six mice. Administration of a high dose of insulin (100 units/kg) resulted in significant decreases of plasma glucose and C-terminal immunoreactive-glucagon (C-GLI) concentrations. Statistical differences from zero-time values were evaluated by Student’s t test: *P < 0.00 1. Plasma glucose and C-terminal immunoreactive glucagon concentrations of lean mice (not illustrated) were significantly decreased by 0.25 unit of insulin/kg.